منابع مشابه
Identification of hepatoprotective flavonolignans from silymarin.
Silymarin, also known as milk thistle extract, inhibits hepatitis C virus (HCV) infection and also displays antioxidant, anti-inflammatory, and immunomodulatory actions that contribute to its hepatoprotective effects. In the current study, we evaluated the hepatoprotective actions of the seven major flavonolignans and one flavonoid that comprise silymarin. Activities tested included inhibition ...
متن کاملA Review on Hepatoprotective Activity of Silymarin
Silymarin is obtained from the seeds of Silybum marianum (milk thistle), an edible plant that has been used medicinally from ancient times for the treatment of various liver disorders. It is widely prescribed by herbalists and has almost no known side effects. The plant is native to the Mediterranean and grows throughout Europe, North America, India, China, South America, Africa and Australia. ...
متن کاملAntioxidant Activity of Hepatoprotective Silymarin and Silybum marianum L. Extract
The paper presents the antioxidant activity evaluation of Silybum marianum L. extract in comparison with the commercial silymarin standard solution (2 mg/mL) and the time-dependent antioxidant capacity by calculating the free radical 2,2-diphenyl-1-pycryl-hydrazyl (DPPH) reaction rate in the presence of these biosystems. The best result was obtained in the case of S. marianum L. extract, with a...
متن کاملHepatoprotective Effect of Silymarin (Silybum marianum) on Hepatotoxicity Induced by Acetaminophen in Spontaneously Hypertensive Rats
This study was aimed to investigate the effect of Silymarin (SLM) on the hypertension state and the liver function changes induced by acetaminophen (APAP) in spontaneously hypertensive rat (SHR). Animals normotensive (N) or hypertensive (SHR) were treated or not with APAP (3 g/kg, oral) or previously treated with SLM. Twelve hours after APAP administration, plasmatic levels of liver function ma...
متن کاملEvaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial
Hepatic toxicity is the most serious adverse effect of anti-tuberculosis drugs. This study was performed to evaluate the efficacy of silymarin as a hepatoprotective herbal agent. In a randomized double blind clinical trial, 70 new cases of pulmonary tuberculosis were divided into two groups. The intervention group was assigned to receive silymarin and the control group received placebo. Tubercu...
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ژورنال
عنوان ژورنال: World Journal of Hepatology
سال: 2014
ISSN: 1948-5182
DOI: 10.4254/wjh.v6.i3.144